Does mocha sauce have caffeine?Īccording to my Starbucks barista daughter, one question they get asked a lot is if mocha sauce has caffeine in it. This limited-time sauce tastes a bit like toasted marshmallows, making it the perfect wintertime sip. In addition, the Starbucks holiday menu almost always includes toasted white chocolate mocha drinks. The regular Starbucks menu features two types of mocha sauce: Then you can build up from there to create lots of delicious flavors. No matter if you’re in the mood for a warm and cozy Caffè Mocha or an iced version, all mochas begin with the same basic ingredients: espresso, chocolate sauce, milk and whipped cream. On the other hand, an iced mocha at Starbucks replaces steamed milk with cold milk, and is served over ice. If desired, you can order an extra hot mocha, steamed to 180℉. The steaming process even brings out some of the milk’s natural sweetness. The milk is steamed to a standard 160℉ and is velvety smooth. Every Starbucks mocha drink is available hot with steamed milk or cold over ice.Ī warm and toasty hot mocha combines freshly brewed shots of Starbucks signature roast espresso with chocolate sauce and steamed milk. Mocha drinks at Starbucks can be enjoyed hot or cold. This is why mochas are an excellent option for new Starbucks customers trying espresso for the first time. In my opinion, the sweetness of chocolate and whipped cream balances the coffee in a magical way. Starbucks mochas are a type of espresso beverage that bring together full-bodied brewed espresso, bittersweet mocha sauce and milk.Įvery mocha drink gets a nice fluffy topping of Starbucks sweetened whipped cream.Īs you can imagine, the robust flavor of dark roast espresso paired with creamy chocolate and milk makes this popular chocolate Starbucks drink like a marriage made in heaven. Seasoned coffee drinkers love Starbucks line-up of mochas too. Starbucks mochas are a favorite among all types of coffee drinkers.Īs a matter of fact, mochas are one of the best options for people new to Starbucks coffee.
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Although pembrolizumab was associated with a trend toward improved survival in other subgroups, the benefit did not reach the prespecified threshold for statistical significance. Pembrolizumab was associated with a statistically significant 27% improvement in OS in the subgroup of patients with high PD-L1 expression, defined as CPS ≥10 (HR, 0.73 p =.0093) ( Table 2). SABCS Highlights from SABCS 2020: New data on CDK4/6 inhibitors, Highlights from SABCS 2021: T-DXd, KEYNOTE-355, PADA-1 Experts Discuss Clinical. The co-primary endpoints were overall survival (OS) and progression-free survival (PFS) in 3 patient cohorts defined by PD-L1 expression: CPS ≥10 ( n = 323), CPS ≥1 ( n = 636), and the intent-to-treat (ITT) study population ( N = 847). Patients were randomly assigned 2:1 to receive pembrolizumab every 3 weeks ( n = 566) or placebo ( n = 281) in addition to nab-paclitaxel, paclitaxel, or gemcitabine/carboplatin. Tumor samples were graded for PD-L1 expression based on the combined positive score (CPS), which measures PD-L1 expression on tumor cells, lymphocytes, and macrophages. The phase III KEYNOTE-355 trial enrolled 847 patients with locally recurrent inoperable or metastatic TNBC that has not been previously treated with chemotherapy in the advanced setting. Javier Cortes, M.D., Ph.D., of the International Breast Cancer Center, presented results from KEYNOTE-355 demonstrating the optimal PD-L1 expression threshold for pembrolizumab benefit in advanced or metastatic TNBC 2. SABCS 2022: HER2-low and HER2-zero triple-negative breast cancer show distinct biological differences. KEYNOTE-355: Pembrolizumab in Locally Advanced or Metastatic TNBC Merck has announced positive results from the Phase 3 KEYNOTE-355 trial investigating pembrolizumab in combination with chemotherapy as first-line treat. The benefit of pembrolizumab was consistent across subgroups, including those defined by disease stage and nodal status. Pembrolizumab added to neoadjuvant and adjuvant therapy was associated with a statistically significant and clinically meaningful 37% improvement in EFS (HR, 0.63 p =.00031) ( Table 1). The co-primary endpoints were pathologic complete response and EFS. Following surgery, patients received 9 additional cycles of adjuvant pembrolizumab or placebo. Patients were randomly assigned 2:1 to receive both neoadjuvant and adjuvant therapy with pembrolizumab 200mg every 3 weeks ( n = 784) or placebo ( n = 390).ĭuring the neoadjuvant phase of the trial, patients received pembrolizumab or placebo in addition to chemotherapy with carboplatin plus paclitaxel for 12 weeks, followed by doxorubicin or epirubicin plus cyclophosphamide for an additional 12 weeks. The phase III KEYNOTE-522 trial enrolled 1,174 patients with newly diagnosed, operable, stage II-III TNBC. Peter Schmid, M.D., Ph.D., of Barts Cancer Institute, presented findings from KEYNOTE-522 showing a 37% improvement in event-free survival (EFS) associated with neoadjuvant and adjuvant pembrolizumab in early-stage TNBC 1. KEYNOTE-522: Pembrolizumab in Early-Stage TNBC Large – 12′ / 30 cm in length For the sake of this guide, standard pizza is 8 inches/20 centimeters, medium pizza is 10 inches/25″ centimeters, and large pizza is 12 inches/30 centimeters in size. What is the size of Domino’s Pizza in India?Ĭustomers who purchase pizza in India can choose from a variety of sizes, including the following: Small – 8′ / 20 cm in height. The firm has more than 16,000 franchisees in more than 85 countries. Medium pizza pies from Domino’s have 12-inch diameters and feed between two and four people. Small pizzas from Domino’s are 10 inches and feed between one and three people. You’ll find a small, medium, and large pizza pies. Domino’s Pizza Domino’s has a few different sizes for its pizzas. Our small pizza is 10 inches and serves 13 people. We cover a few popular pizza chains below. Pizza Sizes Made for Sharing Domino’s pizza sizes make it easy to personalize your pie in a variety of ways. About Domino’s Pizza Domino’s Pizza, founded in 1960, is a worldwide business with headquarters in Ann Arbor, Michigan. You’ll receive a medium pizza with a butteryflavored crust baked golden and crispy, with layers of cheese that go all the way to the edge. The smallest pie is roughly 9.5-inch broad and feeds two to three people with up to six slices. If you look at the sizes available in Europe and the United States, ordinary size equals 10′′, medium 12′′, big 14′′, and extra large 16′′ in diameter. A 12-inch (medium) pie offers eight slices. The diameter of a New York Style pizza is 18′. What is the average size of a large pizza?Ĩ′ is considered personal size, 10′ is considered small, 12′ is considered medium, 14′ is considered big, and 16′ is considered extra-large. For example, pizzas with a larger amount of toppings may have a slightly larger overall diameter than those with fewer toppings. It is important to note that this size varies depending on the toppings and other ingredients. In addition, in India, Domino’s does not provide an extra-large pizza size as an option. The diameter of a medium Domino’s pizza typically ranges from 10 to 12 inches. However, if you are inquiring about India, the standard size is 8 inches, the medium size is 10 inches, and the big size is 12 inches. If you look at the sizes available in Europe and the United States, ordinary size equals 10′′, medium 12′′, big 14′′, and extra large 16′′ in diameter. What is the size of an extra large pizza at Dominos? Typically, a Domino’s pizza comes in sizes ranging from 10 inches small to 16 inches X-large, with thin crust, super-thin crust, and very thin crust being the most popular options. The personal size pizza starts at 5.99, the small size starts at 7.99, the medium starts at 9.99, and the large starts at 11.99. Now that you know the dimensions of each pizza size, let’s take a look at the prices. Large pizzas with a diameter of 14 inches, medium pizzas with a diameter of 12 inches, and tiny pizzas with a diameter of 10 inches are all available options. And finally, the large size is 14 inches in diameter and serves 7-8 people. What is the difference between a big, medium, and ordinary pizza at Domino’s? Dominick’s standard pizza is 8″/20cm in diameter, medium pizza is 10″/25cm in diameter, and large pizza is 12″/30cm in diameter.ĭomino’s sells a significant amount of pizza. “From Stage to Printing House.” Making Shakespeare: From Stage to Page. Shakespeare and the Book. New York: Cambridge University Press, 2001. Selling Shakespeare: Biography, Bibliography, and the Book Trade. New York: Cambridge University Press, 2016. New York: Cambridge University Press, 2013. This is a marveous and heart-warming holiday show for the family. The First Folio of Shakespeare. Folger Shakespeare Library, March 1991.Įrne, Lukas. First Folio continues its season with the world premiere adaptation of one of the most beloved American novels of all time, Louisa May Alcott’s LITTLE WOMEN, adapted by Heather Chrisler and directed by Melanie Keller. Royal Shakespeare Company, “Printing the First Folio”: Books About Shakespeare’s First Folioīlayney, Peter. Learn More about the First Folio Websites and Videos About Printing Shakespeare’s First Folioįirst Folio Facts from the University of Arizona: įolger Shakespeare Library, “Printing 101”: A typical single sheet, so printed and folded, is a “bifolium.” “Folio” refers to the size of a book that results from printing two pages side-by-side on a sheet of paper, front and back, and folding the sheet once vertically. That would determine how many pages would be printed on a single sheet of paper and how many sheets of paper would be folded together to create one “gathering” to be stitched together and possibly bound. Printers also had to decide what size book to produce. Printers were responsible for supplying the paper, and estimated a print job by the number of sheets required. In early modern England, printers described the length of a book by the number of sheets (which we’ll explore below). Today, we would typically describe the length of a book by the number of pages. In addition, you can report side effects to ModernaTX, Inc. Our focus here is on the unexpected ways these pages were printed-out of sequence-in order to assemble the book for reading-in the right sequence. EUA, as appropriate, in the first line of box 18 of the report form. We can spare you all that, as we work with twenty-first century technologies to introduce aspects of seventeenth-century craftsmanship. Early modern printing houses were noisy, smelly, crowded spaces, requiring long hours of repetitive hard labor over the hand-presses. The First Folio was produced in William and Isaac Jaggard’s printing house between 16. And for your peace of mind, the system guides you through all the steps you need to take, so you don’t have to worry about being a tech-wizard! Customers trust the technology’s transparency too, since electronic signatures can be tracked and managed no matter which device you use. So customers want to feel comfortable with their signature and where the document goes.”Įlectronic signature technology like DocuSign exceeds some of the most stringent global security standards and is accepted in over 180 countries around the world. “When people are buying or leasing residential or commercial properties”, says Viljoen, “it’s close to their heart. What your customers are looking for right now is someone they can trust. Real estate is already an emotional experience for customers, but this year has tuned even the simplest experiences into stressful ones. At a recent RE/MAX event, Doris Otto, Head of Digital Strategy at RE/MAX Europe, spoke with Robert Viljoen, Account Executive at DocuSign, to learn about three ways that electronic signature technology is revolutionizing the real estate industry. RE/MAX Europe has partnered with DocuSign as our preferred vendor for electronic signatures. Electronic signatures, also known as e-signatures, help real estate businesses close deals faster, reduce costs and improve the customer experience, all while boosting the number of transactions. So it’s no wonder that electronic signature technology is changing the entire workflow of how documents are signed and processed. And since ink-signed or “wet” signatures need to be faxed, scanned and mailed back and forth from one party to another, this not only takes a lot of time, but opens the door to costly mistakes. In the real estate industry, millions of documents are signed every single day. Making the tech choices that give your customers what they really want. Good luck finding the nog in August though. And as a gift for you, we’ve assembled 65 Christmas songs so incredibly catchy, you just might want to listen all year round. But festive cheer has found its way into pop, hip-hop, R&B, metal, punk, indie… you name it. Free download Duke Football Wallpapers for Desktop, Mobile & Tablet. There is, of course, something of a Christmas canon: ‘All I Want for Christmas is You’ and ‘Fairytale of New York’ are great songs… which is good, as inevitably you’re going to hear them about a million times this holidays. We've gathered more than 5 Million Images uploaded by our users and sorted them by the most popular ones. 1920x1200 Red and blue planet wallpaper'>. 1920x1080 Download 1920x1080 Ring System, Blue Planet, Nebula, Stars'>. But even more cynical later generations of pop have produced plenty of gold. Explore a curated colection of Duke Blue Devils Wallpaper Images for your Desktop, Mobile and Tablet screens. 3840x2160 Blue Planet Space 4k, HD Digital Universe, 4k Wallpaper'>. Louisville: Three takeaways from the Blue Devils incredible win. There are plenty of keepers from the ‘40s-‘70s heyday of the Christmas record as an art form. Duke Blue Devils 1080P, 2K, 4K, 8K HD Wallpapers Must-View Free Duke Blue Devils Wallpaper Images - Don't Miss 100 Free to Use Personalise for all Screen & Devices. Let it exhilarate them.Love them, hate them, or just accept them as a sort of immutable fact of life, Christmas songs are a thing, and as December 25 gets inexorably closer and closer they’re a thing that becomes increasingly inescapable.Īnd although there’s been a fair amount of disposable novelty rubbish written over the years, the reality is that a lot of Christmas songs are bangers. Don’t let the chaos depress your teams, Lansing says. For example, reorienting your operating model around products or adopting an emerging technology such as AI. Discover more Basketball, Duke, Duke Basketball, Duke Blue, Duke Blue Devils. One of the best ways to empower your teams is to encourage them to “find opportunities in the chaos,” Lansing says.īy “chaos” Lansing means something that is out of order - a process, department, tool, or the like - that if put in order presents an opportunity to build a competitive advantage. the logo for duke blue planet com on a black background with white lines and an. “Don’t overlook the correlation between employee satisfaction and customer satisfaction,” he says. In these meetings, teams are encouraged to identify the activities or features of their work they most enjoy, or the enhancements to those activities and features that, if made, would most improve employees’ work lives. Perpetual Planet Perpetual Planet Initiative About Rolex Behind the crown. “Suddenly, you have something on the roadmap you never expected.” Lansing learned this not long after starting these meetings, about ten years ago at a previous employer, where the forums regularly drew 30 to 45 attendees.Īt AccentCare, Lansing has extended the promise of these forums through what he calls “Happiness Hours,” a part of his perennial effort to minimize attrition. Free download Duke Blue Planet The Official Website of Duke Mens Basketball for Desktop, Mobile & Tablet. “You just get people to throw out ideas, then soon enough, everyone’s building on them, talking about ROI and value-creation models and all this stuff,” he adds. The true power of these forums is in their ability to create momentum, Lansing says. The developers of Fast Duplicate File Finder have implemented really comprehensive similarity search algorithms as this tool can find even text documents that have rearranged paragraphs and altered sentences. In order to find similarities, a tool should implement advanced analysis algorithms. Computers are precise digital machines and finding similarities is not something that they can do out of the box. The similar files mode is something that you will not find in other applications. The exact duplicate and equal file size modes don’t need any clarifications. Those include the exact duplicate search mode, similar files mode, similar file names mode, and file size – equal file size mode. It uses an optimized byte-to-byte comparison method which is both fast and reliable. That is because it does not rely on simple CRC or MD5 checksums. It was the only tool in our tests that never produced incorrect results. The first and most important thing is the fact that this tool provides 100% accurate results. Visual Similarity Duplicate Image Finder.Best Duplicate File Finder & Cleaner Tools to Delete Repeating FilesĪll software in the best duplicate finder list below is sorted from BEST to WORST. We will cover the key features that you should consider when choosing a duplicate remover. After all, you don’t want to scan your valuable data with a poor tool that may produce incorrect results and lead to data loss. Choosing the best clone remover is the most important part of the deduplication process. We have provided a comprehensive list of the finest duplicate cleaners both free and paid. A larger quantity of repeatings files means more useless data to be processed by antivirus and all other types of applications leading to slower system performance. They not only occupy space, but they also reduce the performance of your Windows system. Duplicate files may easily build up in many ways – by downloading multiple times, copying, saving in different locations, backing up, and many more. Below we have tested and listed the top 13 best duplicate file finder tools to remove duplicate and similar files. Ratner and Nathanson are exploring many concepts, including the use of the motion capture technique for the possible sequel and various different film projects with Chan and Tucker. In the DVD audio commentary for Rush Hour 3, Brett Ratner joked that the fourth Rush Hour film could be released in 2012. Future īecause of the films' collective box-office success, director Brett Ratner and writer Jeff Nathanson are considering the production of a fourth installment. Additionally, the film was not screened in Chinese theaters in 2007 to make way for a larger variety of foreign films, according to a business representative (The quota for imported films is 20 each year). This film has received an M rating by the Office of Film and Literature Classification (Australia) and a PG-13 rating by the MPAA for "sequences of action violence, sexual content, nudity and language". Tzi Ma reprises his role as Ambassador Han, Lee's boss and friend who appeared in the first installment. Academy Award-winning film director Roman Polanski co-stars as a French police official involved in Lee and Carter's (Chan and Tucker's characters) case. The film, set in Paris and Los Angeles, was first released on August 10, 2007, and grossed $256,585,882 worldwide. Rush Hour 3 was officially announced on May 7, 2006, and filming began on July 4, 2006. New Line Cinema was confident in Ratner's talents, having done Money Talks with him, so they made a hard commitment to a budget and start date for the film. Several studios were interested in acquiring the project. After attaching director Ratner and developing the project for more than a year with producers including Sarkissian and Roger Birnbaum, Disney Studios Chief Joe Roth put the project into turnaround, citing concerns about the $34-million budget, and Chan's appeal to American audiences at the time. The screenplay was sold by LaManna's William Morris agent Alan Gasmer to Hollywood Pictures, a division of the Walt Disney Company, with Arthur Sarkissian attached as producer. Rush Hour began as a spec script written in 1995 by screenwriter/novelist Ross LaManna. For example, the scene where Inspector Lee accidentally grabs Detective Johnson's ( Elizabeth Peña) breasts is a reference to Jackie Chan's film Mr. Director Brett Ratner, a big fan of Jackie Chan's Hong Kong movies, felt that American audiences would not be familiar with the jokes in Jackie's other movies, and deliberately re-used some of his gags. Chris Tucker was finally chosen for the part. Martin Lawrence was originally considered for the role of James Carter. Jackie and Chris discussed working on the movie and commenting on each other.Rush Hour was released on September 18, 1998, grossing $245,300,000 worldwide. Also at the beginning and endings of the commercial breaks, interviews with Jackie Chan and Chris Tucker and scenes from Rush Hour 2 were shown. When aired on television on TBS in 2001, the following alterations were made: usage of the word 'shit' was completely removed and replaced by 'stuff','it', etc., the usage of the word 'ass' was limited The scene at the police station where Carter apologizes to Johnson for spreading rumors at Christmas about them sleeping together and Johnson is enraged, the part where Lee stops her and says that Carter was just kidding and also notices his hands are on Johnson's breasts was removed when Johnson and Lee come to Soo Yung's aide in the van, Johnson's sentence of 'it'll blow if I take it off' was removed many of the outtakes were removed and shortened, like Jackie Chan's "My daddy cotcha bullet by his bare hands, no bullshit." was shortened at the beginning where Clive shows Carter some C4 in his trunk, Carter's response of 'the Iraqis can't even get this shit' was altered (by replacing 'Iraqis' with Americans and removing the word shit). Now let’s see which one you should take to reach Miami or Disneyland. So, this is how you travel to Miami through the I75 route. At Fort Lauderdale, you’ll see that I95 and I75 are colliding together. Keep moving through the I75 and you’ll reach Fort Lauderdale. Keep moving forward and you’ll see the road will turn left towards Miami. From Tampa, if you keep moving south, you’ll reach Fort Myers. Though, if your plan is to go to Miami, you have to keep traveling from Tampa to the south. Route 27 is not an interstate route, but it does connect to the I4 route. This is also a shortcut to Orlando if you take the 27 route. Or if you don’t want to see the Tampa traffic, you can take the bypass route. Also, from Tampa, you can travel a bit more north to Disneyland. Yes, you can take both of these routes to Florida.Īlthough, the I75 route can reach you in Tampa. People also ask, i 77 or I 75 to florida. Though there are debates on I10 and I40 comparison. I10 and I40 connect the whole USA from East to west. Such as I4 you’ll see that i 10 and i 75 intersection in florida map.Īlthough, the I10 is not a small road. But the I75 route is not the fastest route to Miami nor Disneyland. The I75 route is also connected through many different major cities. The I75 route is also coming south from Georgia. But one massive difference is that this area sits on the west coast of Florida. There are a few similarities with the I95 route. Route I75 is another interstate road that connects Florida to other states. So, How about taking that route? Let’s see how that road is in the section below. When you reach Miami, you’ll find route I75 is connected to Miami as well. Afterward, you’ll reach Fort Lauderdale and right after that, you’ll reach Miami. The I95 route will take you to West Palm Beach which continues to Boca Raton. Such as the 27 route.īut if you are planning to go to Miami, continue traveling on the I95. So, if you are scared to take this road, there are other roads to pick from. Though, people say I40 is the most dangerous roads in US. Disneyland will be on your right after you get on the I4. When you reach Daytona Beach, the I4 route will be on your right. To go to Disneyland you have to take the I4 road. Disneyland is located in the middle of Florida in Orlando. If you are planning to go to Disneyland, I95 is the fastest route. So you have to go through the city traffic.Īfter you cross Jacksonville, you will drive beside the sea heading directly to Miami. The first big city which will come up in Jacksonville. I95 roads will take you directly to Miami. Where I75 is located on the west side of Florida. But I95 is located on the east side of Florida. Sometimes there is traffic on route I95.īoth of the roads serve the same purpose. Though do check out the i 75 route from toronto to florida map. You can even take the i 95 to florida from toronto. These interstate roads can even travel internationally. Unlike I70 and I80, I95 and I75 roads connect Florida to other states. Here you will see the i 75 in florida map. If you zoom out on your google map, you’ll see wide roads. Interstate roads are wide and usually don’t have that much traffic. It is also the best way from Albuquerque to New-Mexico. Such as I40 connects many different states together. Interstate roads are which connect a state to the other ones. When it comes to traveling, interstates are one to pick. We take great pride in curating a fun monthly dog subscription box every month so you and your pooch both look forward to what may arrive. This 8oz canvas cotton material personalised dog toy storage basket, hardwearing and good quality great for those toys for a new pup Finished with there name (. 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